GasGasGas - Anaesthetic Science for Anaesthesia!

Isoflurane: Halogenated Volatile Anaesthetic Agent Pharmacology

This Primary FRCA podcast episode introduces you to Isoflurane, a ubiquitous and fairly cheap volatile anaesthetic agent that always seems to be left alone while its sevoflurane friend lives the high life, This episode probably won't sway your use, but if you walk into an anaesthetic halfway thru and have no idea what your ET for MAC-1 is, then this is for you!
GasGasGas - putting knowledge in your brain!
Show notes at: https://gasgasgas.uk/isoflurane/↗
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Introducing Volatile Anaesthetic Agents! MAC, Blood-Gas Solubility & the 'Ideal Agent question'

This Primary FRCA podcast episode introduces you to Volatile anaesthetic agents and the pharmaceutical particulars that make their behaviour through a human very interesting!
We cover Blood gas and oil gas partition coefficients, Saturated vapour pressure, critical temperature and boiling points - and touch on pharmacodynamics and the Viva Question 'What is the ideal anaesthetic agent' approach.
Show notes at: https://gasgasgas.uk/introduction-to-volatile-anaesthetic-agents/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Opioids Quiz: FRCA Primary Exam Viva Practice & Comparison Tables

Yet again, the sound engineer has been sacked........
Apologies that this is a second attempt at an Opioids Quiz, the music cuts went rather wrong - so we've slung the music in the bin!
This is a straight up quiz, with gaps so you can think up an answer and then, as you might expect... an Answer!
The goal isn't to give you verbatim words to regurgitate but to build up these facts in your mind so then next time you cover it you've foundations to build upon!
GasGasGas - putting knowledge in your brain!
Show notes at: https://gasgasgas.uk/clonidine/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Clonidine: Alpha-2 Agonists + Mechanism of Action

Clonidine is a drug found in many a cupboard, acting as a useful adjunct for pain, sedation and having utility in smoothing out post op emergence, it has off license use as a adjunct in regional and neuraxial blockade (at least in the literature!)
Show notes at: https://gasgasgas.uk/clonidine/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Dexmedetomidine in Anaesthesia: Sedation, Anaesthesia & Regional Techniques

Dexemedetomidine is a drug that it seems we are really only just getting our hands on in the UK, it is an Alpha 2 AGOnist causing sedation, anxiolysis and analgesia. 
This episode of GasGasGas explores its use, mechanisms side effect profile and kinetics
Show notes at: https://gasgasgas.uk/dexmedetomidine/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Midazolam: Sedation & peri-Anaesthetic uses + GABA Receptors

Midazolam represents the cornerstone benzodiazepine in perioperative medicine, offering rapid onset sedation, anxiolysis, and amnesia with predictable pharmacokinetics. Understanding its mechanism, dosing strategies, and clinical applications is fundamental for safe anaesthetic practice and optimal patient care.
Show notes @: https://gasgasgas.uk/midazolam/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Etomidate Anaesthesia: Pharma, Adrenal Suppression & Clinical Use

Having an Iota of a Scooby-Doo about Etomidate is perhaps what is required for the FRCA primary exams. We've gone into naturally more detail when we're talking Etomidate for gasgasgas, because we love a bit of detail. This episode covers the pharmacodynamics and pharmacokinetics of Etomidate, but also explores briefly steroidogenesis and what the implications of this is clinically.
GasGasGas - putting knowledge in your brain!
Show note: https://gasgasgas.uk/etomidate-for-the-frca/
Link you must read since this episode! https://www.thebottomline.org.uk/summaries/icm/rsi-ketamine-or-etomidate-for-tracheal-intubation-of-critically-ill-adults/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Stereoisomers & Chirality: Pharmacology Fundamentals for FRCA Primary

Understanding molecular stereochemistry is fundamental to modern anaesthetic practice. The three-dimensional arrangement of atoms within drug molecules directly impacts their pharmacological properties, with some arrangements being therapeutically beneficial while others may be inactive or even harmful. This episode explores the concept of isomerism in anaesthetic drugs, with particular focus on how molecular handedness affects drug choice.
Show notes at: https://gasgasgas.uk/classifying-isomers/ 
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Peri-Neural Local Anaesthetic Adjuncts for Regional Anaesthesia

Welcome to the final local anaesthetic episode - Peri-neural adjuncts- because we should not forget the medley of mixing options that you could stir into your NRfit cauldron.... although most folks don't.
Ketamine, in it goes, give it a stir - a dash of clonidine for a bit of dozy chill - 3 grains of morphia and don't forget the sodium bicarbonate.
Show notes at: https://gasgasgas.uk/peri-neural-adjuncts-to-local-anaesthetics/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Local Anaesthetics Quiz: FRCA Primary Viva Practice Questions

Welcome to an experimental episode of GasGasGas - where you get the joys of a quiz after listening to all these episodes on local anaesthetics agents. Let me know if you think it's dry as hell.
Show notes at: https://gasgasgas.uk/local-anaesthetic-quiz/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025