GasGasGas - Anaesthetic Science for Anaesthesia!

Clonidine: Alpha-2 Agonists + Mechanism of Action

Clonidine is a drug found in many a cupboard, acting as a useful adjunct for pain, sedation and having utility in smoothing out post op emergence, it has off license use as a adjunct in regional and neuraxial blockade (at least in the literature!)
Show notes at: https://gasgasgas.uk/clonidine/
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GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Dexmedetomidine in Anaesthesia: Sedation, Anaesthesia & Regional Techniques

Dexemedetomidine is a drug that it seems we are really only just getting our hands on in the UK, it is an Alpha 2 AGOnist causing sedation, anxiolysis and analgesia. 
This episode of GasGasGas explores its use, mechanisms side effect profile and kinetics
Show notes at: https://gasgasgas.uk/dexmedetomidine/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Midazolam: Sedation & peri-Anaesthetic uses + GABA Receptors

Midazolam represents the cornerstone benzodiazepine in perioperative medicine, offering rapid onset sedation, anxiolysis, and amnesia with predictable pharmacokinetics. Understanding its mechanism, dosing strategies, and clinical applications is fundamental for safe anaesthetic practice and optimal patient care.
Show notes @: https://gasgasgas.uk/midazolam/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Etomidate Anaesthesia: Pharma, Adrenal Suppression & Clinical Use

Having an Iota of a Scooby-Doo about Etomidate is perhaps what is required for the FRCA primary exams. We've gone into naturally more detail when we're talking Etomidate for gasgasgas, because we love a bit of detail. This episode covers the pharmacodynamics and pharmacokinetics of Etomidate, but also explores briefly steroidogenesis and what the implications of this is clinically.
GasGasGas - putting knowledge in your brain!
Show note: https://gasgasgas.uk/etomidate-for-the-frca/
Link you must read since this episode! https://www.thebottomline.org.uk/summaries/icm/rsi-ketamine-or-etomidate-for-tracheal-intubation-of-critically-ill-adults/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Stereoisomers & Chirality: Pharmacology Fundamentals for FRCA Primary

Understanding molecular stereochemistry is fundamental to modern anaesthetic practice. The three-dimensional arrangement of atoms within drug molecules directly impacts their pharmacological properties, with some arrangements being therapeutically beneficial while others may be inactive or even harmful. This episode explores the concept of isomerism in anaesthetic drugs, with particular focus on how molecular handedness affects drug choice.
Show notes at: https://gasgasgas.uk/classifying-isomers/ 
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Peri-Neural Local Anaesthetic Adjuncts for Regional Anaesthesia

Welcome to the final local anaesthetic episode - Peri-neural adjuncts- because we should not forget the medley of mixing options that you could stir into your NRfit cauldron.... although most folks don't.
Ketamine, in it goes, give it a stir - a dash of clonidine for a bit of dozy chill - 3 grains of morphia and don't forget the sodium bicarbonate.
Show notes at: https://gasgasgas.uk/peri-neural-adjuncts-to-local-anaesthetics/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Local Anaesthetics Quiz: FRCA Primary Viva Practice Questions

Welcome to an experimental episode of GasGasGas - where you get the joys of a quiz after listening to all these episodes on local anaesthetics agents. Let me know if you think it's dry as hell.
Show notes at: https://gasgasgas.uk/local-anaesthetic-quiz/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Local Anaesthetics Summary: Complete Review for FRCA Primary Exam

Welcome to another essential episode of Gas Gas Gas, where we summarise all the local anaesthetic content we have covered - In order to get you fired up for the most exciting quiz on local anaesthetics you've ever had the pleasure of listening to.  
Show notes at: https://gasgasgas.uk/comparing-local-anaesthetics/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

LAST: Local Anaesthetic Systemic Toxicity Management for Anaesthetists/Emergency Docs

Welcome to Local Anaesthetic Systemic Toxicity!!
(LAST) is one of the most significant complications in regional anaesthesia practice. This episode explores the pathophysiology, recognition, and management of LAST with particular emphasis on emergency management protocols and risk mitigation strategies. Understanding LAST is crucial for safe regional anaesthesia practice (in Anaesthetic rooms, surgical fields and for emergency department blocks), as it can occur with any local anaesthetic administration and requires immediate, systematic intervention.
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Ropivacaine: The local anaesthetic better than levobupivacaine?

Today we're exploring ropivacaine - the local anaesthetic you might not see every day, but absolutely need to understand when bupivacaine is in short supply or when examiners want to test your knowledge of enantiomeric purity and differential motor blockade....
Show notes at: https://gasgasgas.uk/ropivacaine/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025