GasGasGas - Anaesthetic Science for Anaesthesia!

Lidocaine Pharmacology: Amide Local Anaesthetic not for Spinal Anaesthesia

Welcome to lidocaine - the ubiquitous local anaesthetic that's everywhere in clinical practice but comes with some important caveats. Whether you're preparing for your primary FRCA exams or just starting your anaesthesia rotations, understanding lidocaine's extensive clinical applications, antiarrhythmic properties, and the growing role of IV infusions for pain management is core know how!.
Show notes at: https://gasgasgas.uk/lidocaine/
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GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Prilocaine: Amide Local Anaesthetic - Day Case Champ

Welcome to the Prilocaine episode - the local anaesthetic that's often overshadowed by Bupivacaine but deserves a place in your clinical toolkit. Whether you're preparing for your primary FRCA exams or just starting your anaesthesia rotations, understanding Prilocaine's unique properties will help you tailor anaesthesia to patient and surgery, bupivacaine isn't always the answer
Show notes at: https://gasgasgas.uk/prilocaine-for-the-frca-primary/ 
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Cocaine: Local Anaesthetic Properties & Pharmacology + Hx Spinal Anaesthesia!

If you like a story about tenacious testicular traction and slamming shins then this is the episode for you. 
This FRCA Primary Podcast episode explores cocaine and the exposure patients have to it in the clinical environment, chiefly courtesy of the ENT surgeons. The episode explores mechanism, side effects, onset, implications, but also the history of spinal anaesthesia and treatment of cocaine toxicity in the A&E department. 
Show notes at:https://gasgasgas.uk/cocaine-for-the-frca-primary/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

GasGasGas - Bupivacaine and Friends

This FRCA Primary Podcast episode burrows into bupivacaine, exploring its friends (additives), mechanism of action, and clinical applications. We'll cover the key differences between neuronal and cardiac action potentials, and discuss why levobupivacaine has become the preferred choice in many clinical scenarios.
Show notes at: https://gasgasgas.uk/primary-frca-podcast-episode-31-bupivacaine-and-friends/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

GasGasGas - Introduction to Local Anaesthetics

This FRCA Primary Podcast episode establishes the scientific foundation for understanding how Local Anaesthetic drugs work, why they behave differently and how to use them safely. By the end, you'll understand nerve physiology, sodium channel blockade, drug classification, and the basics of local anaesthetic toxicity.
Show notes at: https://gasgasgas.uk/local-anaesthetic-fundamentals-for-the-frca/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

GasGasGas - Comparing Opioids - Viva Style!

Opioids are a significant cornerstone of anaesthetic practice, forming part of the triad of anaesthesia with their analgesic properties. We utilise these analgesic properties not just because "surgery hurts," but also because our interventions cause physiological upset - laryngoscopy being a prime example.
Show notes at: https://gasgasgas.uk/comparing-opioids-for-the-frca-primary/ 
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

GasGasGas - RemiFentanil and the Minto TCI Model

Remifentanil is an anaesthetist’s dream: ultra-short acting, reliably titratable, and deeply potent. This episode takes a dual-pronged approach, covering both the FRCA-relevant pharmacology of remifentanil and introducing the Minto target-controlled infusion (TCI) model. 
Show notes at: https://gasgasgas.uk/remifentanil-and-minto-tci-model/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Neuraxial Opioid Kinetics: Spinal & Epidural Analgesia for Regional Anaesthesia

In this explainer episode of GasGasGas, we make our descent into the joyful complexities of neuraxial opiate pharmacology.
Why do we bother putting opiates into this space at all? What governs their journey, how do they behave once administered, and what clinical pearls can be drawn from their behaviour? This episode follows the journey of a single opioid molecule through the fatty labyrinth of the epidural space, across barriers, and into its final destination: the dorsal horn of the spinal cord, before it potters away to realms of mischief in the brainstem.
Show notes at: https://gasgasgas.uk/neuraxial-opiate-kinetics-for-the-frca-primary/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Diamorphine (Golden Brown): Opioid Pharmacology for Anaesthetic Practice

In this episode of Gas, Gas, Gas, we drill a figurative oil well into the pharmacology of diamorphine — also known by its more notorious street name, Heroin/Smack/Golden Brown. Diamorphine is a synthetic diacetylated derivative of morphine, and this episode details its mechanism of action, clinical applications, pharmacokinetics, pharmacodynamics, and side effect profile. The episode is structured to support FRCA Primary revision with an irrelevant clinical anecdote (but sound advice I would argue) and exam-focus.
Show notes at: https://gasgasgas.uk/diamorphine-for-the-frca-primary/ 
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025

Oxycodone: Synthetic Opioid Analgesic for Perioperative Pain

We are plunging into the pharmacology of oxycodone, a potent semi-synthetic opioid analgesic widely used in perioperative and chronic pain settings. We explore oxycodone's mechanism of action, pharmacokinetics, and pharmacodynamics
We dissect its action on mu-opioid receptors, compare it to morphine and other opioids, and review evidence regarding oral vs intravenous formulations, metabolism via CYP450 enzymes + implications for renal and hepatic impairment.
It's lost is license for prolonged release versions in acute pain!
Show notes at: https://gasgasgas.uk/oxycodone-for-the-frca-primary/
================================================
GasGasGas - Covering Anaesthetic Science for Anaesthetists!
Sponsored by Teach Me Anaesthetics
Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate]
Contributions to keep the lamps lit here
================================================
Dr Gas Lurks On: 
> BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social)
> X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X
> FaceBook: Facebook - Gas Gas Gas
> Website: www.gasgasgas.uk
================================================
Disclaimer / Sage Advice
> All content is educational in nature and never intended to be acted upon.
> This information is not a suitable substitute for medical advice.
> Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. 
> Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.
================================================
Music Credit: Streets of Sant Ivo - Mid-Air Machine - Free music archive 
Sassy Jazzy - La Faena - Free music archive
================================================
"This podcast and all its content, including but not limited to audio recordings, show notes, artwork, and branding elements, are protected by copyright laws. All rights reserved. No part of this podcast may be reproduced, distributed, or transmitted without prior written permission from the copyright holder."
© GasGasGas-Podcast 2025